Grand Mercure Roxy Hotel were appointed the official hotel for the following major events or groups:
2009
- 1st Asian Youth Games 2009 International Technical Officers
- AVIVA Ironman 70.3 Singapore Triathlon
- First Singapore Tattoo Show
2008
- AVIVA Ironman 70.3 Singapore Triathlon
- Australia Swimming Team
- Canadian Beijing Olympics Athletics Team
- Canadian Beijing Olympics Soccer Team
- CIMB Women Masters Squash 2008
- National Basketball League Teams from Australia, New Zealand, Indonesia, Philippines and Malaysia
- OSIM International Triathlon Participants
- Singapore Disability Sports Council (SDSC) World Skud Championship
- Singapore Disability Sports Council (SDSC) 2nd Singapore Invitational Boccia Open Championship
- USA Pentathlon Team
- Wakeboard World Cup
2007
- British Swimming Team
- Canadian Beijing Olympics Athletics Team
- Canadian Beijing Olympics Soccer Team
- Contender Asia
- IODA Asian Sailing Championship
- National Basketball League Teams from Australia, New Zealand, Indonesia, Philippines and Malaysia
- Wakeboard World Cup